WebJan 1, 2011 · In 1997, Yeh et al re- ported the outcomes of first- and second-line chemotherapy with 24-hour infusion of high- dose 5-FU/LV (HDFL) in 42 mCRC patients. 1 The weekly HDFL regimen consisted of 5-FU (2600 mg/m 2 /week) and LV (300 mg/m 2 /week) administered over a 24-hour period. WebMar 15, 2005 · Further, an HDFL regimen has repeatedly been demonstrated to cause minimal myelosuppression and therefore is an ideal component for combination …
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Webweekly gemcitabine plus HDFL is modestly active with acceptable treatment-related toxicity for patients with advanced CBT. British Journal of Cancer (2004) 90, 1715–1719. doi:10.1038/sj.bjc ... WebBackground: Patients with advanced esophageal cancer are frequently not indicated for intensive chemotherapy due to aero-digestive tract complications. In order to improve the therapeutic index of systemic chemotherapy for these patients, we designed a weekly MP-HDFL protocol, which took advantage of the low toxicity of the infusional dosing schedule … mail file picker ui host
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WebJun 20, 2006 · All patients received HDFL-based chemotherapy as the initial treatment. Seventeen of them showed significant improvement in both clinical symptoms and laboratory abnormalities of DIC. The median overall survival (OS) of the whole group of patients since the diagnosis of DIC or bone marrow metastasis was 7 months (range: 1 week–3 years). WebMar 1, 2008 · They received a total of 855 and an average of 20.4 (4 to 65) courses of HDFL chemotherapy. Most patients were treated at outpatient clinics and the drugs were infused by an ambulatory pump system ... WebDec 29, 2001 · The patients were nonrandomly allocated to 2 treatment groups of either with or without high‐dose 5‐fluorouracil plus leucovorin chemotherapy (HDFL: 5‐Fu: 2,600 mg/m 2 leucovorin 300 mg/m maximum 500 mg). Each treatment group was further divided into 2 subgroups according to the status of p53 overexpression. oak furniture land galway range