WebNov 4, 2024 · Official answer. by Drugs.com. You should not drink grapefruit juice with simvastatin because it can significantly increase blood levels of simvastatin and increase the risk of side effects such as liver damage and a condition called rhabdomyolysis, which is the excessive breakdown of muscle tissue. Occasionally, rhabdomyolysis can cause kidney ... WebMar 5, 2013 · Our research group discovered the interaction between grapefruit and certain medications more than 20 years ago. 1 – 3 Currently, more than 85 drugs, most of which are available in Canada, are known or predicted to interact with grapefruit. This interaction enhances systemic drug concentration through impaired drug metabolism.

Grapefruit Warning: It Can Interact with Common …

WebJul 1, 2007 · Eating grapefruit or drinking grapefruit juice affects how your body processes certain medicines. The chemicals in grapefruit can cause your body to absorb either too much or too little medicine into your bloodstream. This makes it more likely that you will experience side effects from the medicine, or that your medicine won’t be effective. WebFor drugs recently sold on the market, drugs have information pages (monographs) that provide information on any potential interaction between a medication and grapefruit juice. Because there is a growing number of medications that are known to interact with citrus, [1] patients should consult a pharmacist or physician before consuming citrus ... shards dashboard lite react

Grapefruit and Metformin: Is It Safe? - Healthline

WebThe U.S. Food and Drug Administration has required that some prescription and over-the-counter (OTC) drugs generally taken by mouth include warnings against drinking grapefruit juice or eating grapefruit while taking the drug. Here are examples of some types of drugs that grapefruit juice can cause problems (interact) with: WebDec 26, 2024 · How Does Grapefruit Juice Interact with Medications? Many drugs are processed by an enzyme called cytochrome P450 3A4 (CYP3A4). Grapefruit juice inhibits this enzyme. When the enzyme can’t process the medication as efficiently, the drug levels can build up, causing worsened or more severe side effects. WebNov 6, 2024 · Most Americans who drink grapefruit juice do so for breakfast-- a time of day when many people also take medications.Grapefruit juice, it turns out, can affect some … shards d3